Game highlights: The top four teams in the Big Ten in the conference championship
Michigan State beat Michigan on Saturday, 24-20, to claim the Big 12 title.
It was the fifth Big Ten title game this season.
Michigan won the conference title in 2015, and the Spartans have won four straight in conference play.
The Wolverines will play at Wisconsin in the regular season finale.
Purdue beat Iowa State 24-16 on Saturday to take the MAC title.
Indiana beat Purdue 34-26 on Saturday.
Indiana is coming off a 34-31 victory over Michigan State last season.
Iowa State beat Indiana 34-24 on Saturday in the most recent meeting.
Purdue won the MAC West Division title last season with a 29-10 victory over Iowa State.
Michigan State is in the playoff picture with a 16-4 record and a chance to make the NCAA Tournament.
Indiana and Iowa State will meet in the first round of the NCAA tournament on Monday in Cincinnati.
The Big Ten is down to its final two teams and has one win from its final four games.
The conference is playing for its sixth straight title, which would put it at 9-1 overall and 8-1 in the MAC.
The Big Ten East is in a tie for third in the country with two teams advancing.
Illinois is in second with a 14-5 record.
Purdue is in third with a 10-4 mark.
Ohio State and Penn State are tied for fourth in the league with nine wins apiece.
Indiana, Iowa State, Purdue and Michigan State are in fifth with nine games remaining.
The ACC is in eighth with seven teams remaining.